Puerto San Judas was the main port of Isla Fortuna in the Caribbean. It was named after Jude, the patron saint of desperate situations.

The town contained a butcher's shop, an apothecary, a dairy and a fishmonger's. It also contained an inn known for selling gumbo. A wooden church was built in honor of Saint Jude.

The town's population was vanished by the Sword of Cortés, and the dock destroyed by Jack Sparrow while under the influence of the spirit of Hernán Cortés. However, the townspeople were returned to the world after Montecuhzoma's spirit was released to defeat Cortés.